BACKGROUND: Atypical fibroxanthoma (AFX) is an uncommon spindle cell neoplasm occurring most often in actinically damaged skin of elderly patients. This tumor has invasive potential, may recur locally after excision, and rarely metastasizes.

2018-04-15

2020-10-14 A comparison of Mohs micrographic surgery and wide excision for the treatment of atypical fibroxanthoma. Dermatol Surg 1997;23:105-110. PubMed 8. Jacobs DS, Edwards WD, Ye RC. Metastatic atypical fibroxanthoma of skin. Cancer 1975;35:457-463.

Background. Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. Atypical fibroxanthoma (AFX) AFX is best treated by complete surgical excision, with Mohs micrographic surgery considered the treatment of choice. Metastasis rarely occurs, but there is a high rate of local recurrence, especially in patients who are immunosuppressed. Treatment of atypical fibroxanthoma of the skin (AFX) includes curettage and dessication (C&D), wide local excision (WLE), and Mohs micrographic surgery (MMS).

Atypical fibroxanthoma of the medial canthus treated by Mohs Micrographic Surgery. Prativa SA Jayasekera 1* Stuart A Osborne 2 James AA Langtry 3 . 1 Royal Victoria Infirmary, Newcastle upon Tyne BM Medicine MRCP DERM, England, UK 2 Sunderland …

The lumps may be pink or red in colour. They can be ulcerated or crusted.

Atypical fibroxanthoma is a type of skin cancer that typically occurs on the head and neck of older people who have had lots of sun damage. It is not usually thought of with the more common skin cancers, such as basal or squamous cell carcinomas, but it is considered to be skin cancer. Atypical fibroxanthoma usually appear as pink-red raise areas

Once enough cells are produced to replace the old ones, normal cells stop dividing.

It is not usually thought of with the more common skin cancers, such as basal or squamous cell carcinomas, but it is considered to be skin cancer.
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( AFX) Atypical fibroxanthoma is a type of tumor that effects primarily in older With Mohs micrographic surgery the recurrence was 0%, and with wide local excision it was 8.7%. WLE with 2 cm margins was recommended to ensure 96.6 % The tumor was diagnosed as atypical fibroxanthoma (AFX). Mohs micrographic surgery was performed in May 2006 and no recurrence was noted in one year of Mohs Micrographic Surgery differs from wide local excision in that it removes skin cancer one small layer at a time.

What is the outcome for atypical fibroxanthoma? Background: Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy.
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2020-10-14

Dudelzak J(1), Sheehan DJ, Mullins SC, Peterson CM. Author information: (1)Division of Dermatology, Department of Medicine, Augusta, Georgia 30912, USA. Atypical fibroxanthoma (AFX) is a rare, rapidly growing mesenchymal neoplasm that often presents on sun-exposed head and neck regions of older individuals. The diagnosis relies on knowledge of its clinical and histological features combined with immunohistochemistry markers used primarily to exclude other cutaneous neoplasms that may share Atypical fibroxanthoma (AFX) is the most common of the rare cutaneous malignancies.

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Histologically, it can be distinguished from atypical fibroxanthoma by the The best results are obtained with wide local excision or Mohs micrographic surgery

A regular follow‐up is recommended. © 2014 Wiley Periodicals, Inc. Head Neck 37: 829–834, 2015 Atypical fibroxanthoma (AFX) is the most common of the rare cutaneous malignancies. AFX usually involves sites of high cumulative ultraviolet exposure and is rarely located in the periocular region. We are aware of 7 case reports in the literature, of periocular AFX, one of which was treated with Mohs Micrographic Surgery (MMS). Seavolt M, McCall M (2006) Atypical fibroxanthoma: review of the literature and summary of 13 patients treated with mohs micrographic surgery. Dermatol Surg 32: 435-441.

31 May 2014 Fibrous Tissue Abnormalities – Atypical Fibroxanthoma. May 31st Treatment typically involves surgical removal with Mohs surgery. Atypical

Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential.

Note that atypical fibroxanthoma is a dermal-based process, while spindle cell squamous cell carcinoma variants (on the differential diagnosis) connect with the epidermis and show signs of keratinization. 2021-04-07 · Atypical fibroxanthoma relapse as pleomorphic dermal sarcoma after slow Mohs micrographic surgery. Large trials comparing Mohs to standard excision for other types of skin cancer are lacking. In Mohs surgery, tumour cells must be accurately identified on microscopic examination of frozen sections. This can be challenging in some skin cancers, such as: Atypical fibroxanthoma; Very poorly differentiated squamous cell carcinoma AFX will most commonly appear on the head and neck of elderly patients.